Inflammation and men's fertilityInflammation seems to be the buzz word among all the health gurus nowadays. It seems to be responsible for everything from cancer to infertility. Here is an article about how men can be affected by a pro-inflammatory substance call MIF. This substance seems to be found in people who have inflammatory diseases and autoimmune diseases. I have known a number of people with autoimmune disease who were able to control it (even without medication) by eating an "anti-inflammatory diet. Most of the foods I recommend for fertility (see (see fertility foods - getpregnantover40.com) are anti-inflammatory.
Yousef Al-Abed, PhD, and his colleagues at The Feinstein Institute for Medical Research have isolated an immune substance called macrophage migration inhibitory factor (MIF) in semen samples from infertile and reproductively healthy men. MIF is key to helping sperm mature, which is necessary for its union with an egg. The finding could lead to a diagnostic test to determine fertility status.
The study appears in the latest issue of Molecular Medicine. The semen samples were collected from men three to five days after a period of sexual abstinence. The scientists had no idea when analyzing levels of MIF whether the sample came from any of the 68 men who had problems conceiving or from the 27 healthy controls. The findings have a Goldilocks kind of quality: Those with infertility problems had MIF levels that were either too high or too low. Those who had no problems conceiving had levels that were just right.